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This article will tell you about Budd-Chiari syndrome.

This article will tell you about Budd-Chiari syndrome.

Budd-Chiari syndrome is a series of clinical manifestations caused by obstruction of hepatic veins.

Budd-Chiari syndrome is a retrohepatic portal hypertension characterized by hypertension of inferior vena cava caused by an obstructive lesion of superior inferior vena cava from various causes. In acute phase, patient had fever, pain in right hypochondrium, a large amount of peritoneal effusion, jaundice, hepatomegaly, pain in liver, oliguria. The disease is more common in young men, ratio of men and women is approximately (1.2-2):1, age 2.5-75 years, most often - 20-40 years.

This article will tell you about Budd-Chiari syndrome. cause
  • Primary (75%) - hepatic vein thrombosis.
  • Secondary (25%): compression of hepatic vein by an external structure (eg, tumor)
  • Many patients (10-40%) develop Budd-Chiari syndrome as a complication of polycythemia (a disorder in proliferation of red blood cells).
  • Patients with paroxysmal nocturnal hemoglobinuria (PNH) appear to be more prone to Budd-Chiari syndrome than to other types of thromboembolic disease: up to 40% of patients may develop Budd-Chiari as well as cerebrovascular accidents.
    • This article will tell you about Budd-Chiari syndrome. pathophysiology

    Any blockage of hepatic venous vessels is called Budd-Chiari syndrome, from venules to right atrium.

    This article will tell you about Budd-Chiari syndrome. Signs and symptoms

    The syndrome is characterized by rapidly progressive abdominal pain, hepatomegaly (hepatomegaly), ascites, and later symptoms of liver dysfunction: elevated liver enzymes, encephalopathy.

    It also recognizes a slowly developing form of hepatic vein occlusion, which may be painless.

    This article will tell you about Budd-Chiari syndrome.

    Patients are commonly known to have a tendency to form blood clots, and Budd-Chiari syndrome may be first symptom of this tendency.

    Diagnostics

    If Budd-Chiari syndrome is suspected, measure levels of liver enzymes and other organ markers (creatinine, urea, electrolytes, LDH).

    Budd-Chiari syndrome is diagnosed by abdominal ultrasound, although sometimes a more invasive method (retrograde angiography) is required. A liver biopsy is sometimes needed to differentiate Budd-Chiari syndrome from other causes of hepatomegaly and ascites, such as galactosemia or Reye's syndrome.

    This article will tell you about Budd-Chiari syndrome. address

    With anticoagulants such as warfarin.

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